Vinit Mahajan, M.D., Ph.D. of the University of Iowa recently published an enlightening case concerning a patient whose eyesight was restored thanks to proteomics. The patient presented with uveitis, a potentially blinding condition, whose cause is difficult to diagnose. In the February 11th issue of the journal JAMA Ophthalmology, the UI team describes how they used proteomics to analyze fluid from the affected eye and compare it to protein pattern found in other eyes. It was discovered that, although the patient did not exhibit many of the typical symptoms, they did in fact have a certain autoimmune disorder that affects the retina. Armed with this diagnosis, the team was able to administer the known treatment for this disorder, thus recovering the patient’s sight.
In the Science Daily article The future of precision medicine, Dr. Mahajan stated,
We were able to combine surgery and science and intelligently go back to the patient to decide on the optimal therapy,” Mahajan says. “This is personalized precision medicine. It’s the next step
Proteomics continues to be studied for the purposes of diagnostics in various fields. As mentioned in the Cancer Network (home of the journal Oncology) article Is Personalized Medicine Here? proteomics are being used to study urine from prostate cancer patients, “which has led to the discovery of novel protein markers and protein profiles with potential utility as screening or prognostic tools.”
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